White Matter Integrity on DTI, Amyloid Load, and Neurodegeneration in Non-demented Elderly

IMPORTANCE: Pathophysiologic mechanisms leading to loss of white matter (WM) integrity and the temporal positioning of biomarkers of WM integrity relative to the biomarkers of gray matter (GM) neurodegeneration and amyloid load in the course of AD are poorly understood. OBJECTIVE: To investigate the...

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Publicat a:JAMA Neurol
Autors principals: Kantarci, Kejal, Schwarz, Christopher G., Reid, Robert, Przybelski, Scott A., Lesnick, Timothy, Zuk, Samantha M., Senjem, Matthew L., Gunter, Jeffrey L., Lowe, Val, Machulda, Mary M., Knopman, David S., Petersen, Ronald C., Jack, Clifford R.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810441/
https://ncbi.nlm.nih.gov/pubmed/25347157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2014.1482
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