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Urate crystals directly activate the T-cell receptor complex and induce T-cell proliferation
Uric acid is a known danger associated molecular pattern molecule able to induce inflammation following internalization of its crystals by cells of the innate immune system. By activating antigen-presenting cells, urate boosts adaptive immunity as well. Furthermore, urate crystals can induce prolife...
Gespeichert in:
| Veröffentlicht in: | Biomed Rep |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
D.A. Spandidos
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5649536/ https://ncbi.nlm.nih.gov/pubmed/29085633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/br.2017.960 |
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