Spontaneous Loss of Virulence in Natural Populations of Listeria monocytogenes

The pathogenesis of Listeria monocytogenes depends on the ability of this bacterium to escape from the phagosome of the host cells via the action of the pore-forming toxin listeriolysin O (LLO). Expression of the LLO-encoding gene (hly) requires the transcriptional activator PrfA, and both hly and p...

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Dettagli Bibliografici
Pubblicato in:Infect Immun
Autori principali: Maury, Mylène M., Chenal-Francisque, Viviane, Bracq-Dieye, Hélène, Han, Lei, Leclercq, Alexandre, Vales, Guillaume, Moura, Alexandra, Gouin, Edith, Scortti, Mariela, Disson, Olivier, Vázquez-Boland, José A., Lecuit, Marc
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
Soggetti:
Molecular Genomics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649026/
https://ncbi.nlm.nih.gov/pubmed/28827366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00541-17
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