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Spontaneous Loss of Virulence in Natural Populations of Listeria monocytogenes

The pathogenesis of Listeria monocytogenes depends on the ability of this bacterium to escape from the phagosome of the host cells via the action of the pore-forming toxin listeriolysin O (LLO). Expression of the LLO-encoding gene (hly) requires the transcriptional activator PrfA, and both hly and p...

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Detalles Bibliográficos
Publicado en:Infect Immun
Main Authors: Maury, Mylène M., Chenal-Francisque, Viviane, Bracq-Dieye, Hélène, Han, Lei, Leclercq, Alexandre, Vales, Guillaume, Moura, Alexandra, Gouin, Edith, Scortti, Mariela, Disson, Olivier, Vázquez-Boland, José A., Lecuit, Marc
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649026/
https://ncbi.nlm.nih.gov/pubmed/28827366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00541-17
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