Type Three Secretion System-Dependent Microvascular Thrombosis and Ischemic Enteritis in Human Gut Xenografts Infected with Enteropathogenic Escherichia coli

Enteropathogenic Escherichia coli (EPEC) is a leading cause of severe intestinal disease and infant mortality in developing countries. Virulence is mediated by a type three secretion system (T3SS), causing the hallmark attaching and effacing (AE) lesions and actin-rich pedestal formation beneath the...

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Veröffentlicht in:Infect Immun
Hauptverfasser: Nissim-Eliraz, Einat, Nir, Eilam, Shoval, Irit, Marsiano, Noga, Nissan, Israel, Shemesh, Hadar, Nagy, Nandor, Goldstein, Allan M., Gutnick, Michael, Rosenshine, Ilan, Yagel, Simcha, Shpigel, Nahum Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Bacterial Infections
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649022/
https://ncbi.nlm.nih.gov/pubmed/28784929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00558-17
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