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NF-kappa-B activation unveils the presence of inflammatory hotspots in human gut xenografts

The single-epithelial cell layer of the gut mucosa serves as an essential barrier between the host and luminal microflora and plays a major role in innate immunity against invading pathogens. Nuclear factor kB (NF-κB), a central component of the cellular signaling machinery, regulates immune respons...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Nissim-Eliraz, Einat, Nir, Eilam, Marsiano, Noga, Yagel, Simcha, Shpigel, Nahum Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092666/
https://ncbi.nlm.nih.gov/pubmed/33939711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0243010
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