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Fatal Pertussis in the Neonatal Mouse Model Is Associated with Pertussis Toxin-Mediated Pathology beyond the Airways

In infants, Bordetella pertussis can cause severe disease, manifested as pronounced leukocytosis, pulmonary hypertension, and even death. The exact cause of death remains unknown, and no effective therapies for treating fulminant pertussis exist. In this study, a neonatal mouse model of critical per...

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Détails bibliographiques
Publié dans:Infect Immun
Auteurs principaux: Scanlon, Karen M., Snyder, Yael G., Skerry, Ciaran, Carbonetti, Nicholas H.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649019/
https://ncbi.nlm.nih.gov/pubmed/28784932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00355-17
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