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Fatal Pertussis in the Neonatal Mouse Model Is Associated with Pertussis Toxin-Mediated Pathology beyond the Airways
In infants, Bordetella pertussis can cause severe disease, manifested as pronounced leukocytosis, pulmonary hypertension, and even death. The exact cause of death remains unknown, and no effective therapies for treating fulminant pertussis exist. In this study, a neonatal mouse model of critical per...
Enregistré dans:
Publié dans: | Infect Immun |
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Auteurs principaux: | , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
American Society for Microbiology
2017
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5649019/ https://ncbi.nlm.nih.gov/pubmed/28784932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00355-17 |
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