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Fatal Pertussis in the Neonatal Mouse Model Is Associated with Pertussis Toxin-Mediated Pathology beyond the Airways

In infants, Bordetella pertussis can cause severe disease, manifested as pronounced leukocytosis, pulmonary hypertension, and even death. The exact cause of death remains unknown, and no effective therapies for treating fulminant pertussis exist. In this study, a neonatal mouse model of critical per...

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Bibliografiset tiedot
Julkaisussa:Infect Immun
Päätekijät: Scanlon, Karen M., Snyder, Yael G., Skerry, Ciaran, Carbonetti, Nicholas H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649019/
https://ncbi.nlm.nih.gov/pubmed/28784932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00355-17
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