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DNA methylation and hydroxymethylation analyses of the active LINE-1 subfamilies in mice
Retrotransposon long interspersed nuclear element-1 (LINE-1) occupies a large proportion of the mammalian genome, comprising approximately 100,000 genomic copies in mice. Epigenetic status of the 5′ untranslated region (5′-UTR) of LINE-1 is critical for its promoter activity. DNA methylation levels...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5648895/ https://ncbi.nlm.nih.gov/pubmed/29051587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14165-7 |
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