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A role of ADAR2 and RNA editing of glutamate receptors in mood disorders and schizophrenia
BACKGROUND: Pre-mRNAs of 2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propanoic acid (AMPA)/kainate glutamate receptors undergo post-transcriptional modification known as RNA editing that is mediated by adenosine deaminase acting on RNA type 2 (ADAR2). This modification alters the amino acid sequenc...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3902024/ https://ncbi.nlm.nih.gov/pubmed/24443933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-7-5 |
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