A role of ADAR2 and RNA editing of glutamate receptors in mood disorders and schizophrenia

BACKGROUND: Pre-mRNAs of 2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propanoic acid (AMPA)/kainate glutamate receptors undergo post-transcriptional modification known as RNA editing that is mediated by adenosine deaminase acting on RNA type 2 (ADAR2). This modification alters the amino acid sequenc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kubota-Sakashita, Mie, Iwamoto, Kazuya, Bundo, Miki, Kato, Tadafumi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2014
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902024/
https://ncbi.nlm.nih.gov/pubmed/24443933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-7-5
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