CryoEM structure of Saccharomyces cerevisiae U1 snRNP offers insight into alternative splicing

U1 snRNP plays a critical role in 5ʹ-splice site recognition and is a frequent target of alternative splicing factors. These factors transiently associate with human U1 snRNP and are not amenable for structural studies, while their Saccharomyces cerevisiae (yeast) homologs are stable components of U...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Li, Xueni, Liu, Shiheng, Jiang, Jiansen, Zhang, Lingdi, Espinosa, Sara, Hill, Ryan C., Hansen, Kirk C., Zhou, Z. Hong, Zhao, Rui
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648754/
https://ncbi.nlm.nih.gov/pubmed/29051543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01241-9
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