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NLRP3 and potassium efflux drive rapid IL-1β release from primary human monocytes during Toxoplasma gondii infection
IL-1β is produced by myeloid cells and acts as a critical mediator of host defense during infection and injury. We found that the intracellular protozoan parasite Toxoplasma gondii induced an early IL-1β response (within 4 hr) in primary human peripheral blood monocytes isolated from healthy donors....
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| Udgivet i: | J Immunol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5648586/ https://ncbi.nlm.nih.gov/pubmed/28904126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700245 |
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