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Human Innate Immunity to Toxoplasma gondii Is Mediated by Host Caspase-1 and ASC and Parasite GRA15

Interleukin-1β (IL-1β) functions as a key regulator of inflammation and innate immunity. The protozoan parasite Toxoplasma gondii actively infects human blood monocytes and induces the production of IL-1β; however, the host and parasite factors that mediate IL-1β production during T. gondii infectio...

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Hlavní autoři: Gov, Lanny, Karimzadeh, Alborz, Ueno, Norikiyo, Lodoen, Melissa B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Microbiology 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3705447/
https://ncbi.nlm.nih.gov/pubmed/23839215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00255-13
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