Thymosin β4 alleviates renal fibrosis and tubular cell apoptosis through TGF-β pathway inhibition in UUO rat models

BACKGROUND: Thymosin β4 (Tβ4) is closely associated with the cytoskeleton, inflammation, wound healing, angiogenesis, apoptosis, and myocardial regeneration, but the effects of Tβ4 treatment on chronic renal tubular interstitial fibrosis (CRTIF) are poorly known. This study aimed to examine the effe...

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Veröffentlicht in:BMC Nephrol
Hauptverfasser: Yuan, Jing, Shen, Yan, Yang, Xia, Xie, Ying, Lin, Xin, Zeng, Wen, Zhao, Yingting, Tian, Maolu, Zha, Yan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648500/
https://ncbi.nlm.nih.gov/pubmed/29047363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-017-0708-1
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