Thymosin β4 alleviates renal fibrosis and tubular cell apoptosis through TGF-β pathway inhibition in UUO rat models

BACKGROUND: Thymosin β4 (Tβ4) is closely associated with the cytoskeleton, inflammation, wound healing, angiogenesis, apoptosis, and myocardial regeneration, but the effects of Tβ4 treatment on chronic renal tubular interstitial fibrosis (CRTIF) are poorly known. This study aimed to examine the effe...

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Detalhes bibliográficos
Publicado no:BMC Nephrol
Main Authors: Yuan, Jing, Shen, Yan, Yang, Xia, Xie, Ying, Lin, Xin, Zeng, Wen, Zhao, Yingting, Tian, Maolu, Zha, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648500/
https://ncbi.nlm.nih.gov/pubmed/29047363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-017-0708-1
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