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Adeno-associated virus-mediated neuroglobin overexpression ameliorates the N-methyl-N-nitrosourea-induced retinal impairments: a novel therapeutic strategy against photoreceptor degeneration

Retinal degeneration (RD) is a heterogeneous group of inherited dystrophies leading to blindness. The N-methyl-N-nitrosourea (MNU)-administered mouse is used as a pharmacologically induced RD animal model in various therapeutic investigations. The present study found the retinal neuroglobin (NGB) ex...

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Publicat a:Ther Clin Risk Manag
Autors principals: Tao, Ye, Yang, Zhen, Fang, Wei, Ma, Zhao, Huang, Yi Fei, Li, Zhengwei
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648317/
https://ncbi.nlm.nih.gov/pubmed/29075122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TCRM.S144822
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