Susceptibility to N-methyl-N-nitrosourea-induced retinal degeneration in different rat strains

To evaluate the potential role of genetic background in the susceptibility to retinal degeneration induced by N-methyl-N-nitrosourea (MNU), female rats of the Sprague-Dawley (SD), Long-Evans (LE) and Copenhagen (CH) strains were administered 50 mg/kg MNU or saline at 7 weeks of age. Retina morpholog...

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Pubblicato in:J Toxicol Pathol
Autori principali: Emoto, Yuko, Yoshizawa, Katsuhiko, Kinoshita, Yuichi, Yuki, Michiko, Yuri, Takashi, Tsubura, Airo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Japanese Society of Toxicologic Pathology 2015
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Short Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766522/
https://ncbi.nlm.nih.gov/pubmed/26989305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.2015-0062
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