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A kinase inhibitor library screen identifies novel enzymes involved in ototoxic damage to the murine organ of Corti

Ototoxicity is a significant side effect of a number of drugs, including the aminoglycoside antibiotics and platinum-based chemotherapeutic agents that are used to treat life-threatening illnesses. Although much progress has been made, the mechanisms that lead to ototoxic loss of inner ear sensory h...

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Pubblicato in:PLoS One
Autori principali: Ryals, Matthew, Pak, Kwang, Jalota, Rahul, Kurabi, Arwa, Ryan, Allen F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648133/
https://ncbi.nlm.nih.gov/pubmed/29049311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186001
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