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The α-Tubulin gene TUBA1A in Brain Development: A Key Ingredient in the Neuronal Isotype Blend

Microtubules are dynamic cytoskeletal polymers that mediate numerous, essential functions such as axon and dendrite growth and neuron migration throughout brain development. In recent years, sequencing has revealed dominant mutations that disrupt the tubulin protein building blocks of microtubules....

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Pubblicato in:J Dev Biol
Autori principali: Aiken, Jayne, Buscaglia, Georgia, Bates, Emily A., Moore, Jeffrey K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648057/
https://ncbi.nlm.nih.gov/pubmed/29057214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jdb5030008
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