Polycomb directs timely activation of germline genes in spermatogenesis

During spermatogenesis, a large number of germline genes essential for male fertility are coordinately activated. However, it remains unknown how timely activation of this group of germline genes is accomplished. Here we show that Polycomb-repressive complex 1 (PRC1) directs timely activation of ger...

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Détails bibliographiques
Publié dans:Genes Dev
Auteurs principaux: Maezawa, So, Hasegawa, Kazuteru, Yukawa, Masashi, Sakashita, Akihiko, Alavattam, Kris G., Andreassen, Paul R., Vidal, Miguel, Koseki, Haruhiko, Barski, Artem, Namekawa, Satoshi H.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2017
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647939/
https://ncbi.nlm.nih.gov/pubmed/28924034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.302000.117
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