Prazosin during threat discrimination boosts memory of the safe stimulus

The α-1 adrenoreceptor antagonist prazosin has shown promise in the treatment of post-traumatic stress disorder (PTSD) symptoms, but its mechanisms are not well understood. Here we administered prazosin or placebo prior to threat conditioning (day 1) and tested subsequent extinction (day 2) and reex...

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Bibliographic Details
Published in:Learn Mem
Main Authors: Homan, Philipp, Lin, Qi, Murrough, James W., Soleimani, Laili, Bach, Dominik R., Clem, Roger L., Schiller, Daniela
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2017
Subjects:
Brief Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647929/
https://ncbi.nlm.nih.gov/pubmed/29038221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.045898.117
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