Prazosin during threat discrimination boosts memory of the safe stimulus

The α-1 adrenoreceptor antagonist prazosin has shown promise in the treatment of post-traumatic stress disorder (PTSD) symptoms, but its mechanisms are not well understood. Here we administered prazosin or placebo prior to threat conditioning (day 1) and tested subsequent extinction (day 2) and reex...

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Foilsithe in:Learn Mem
Main Authors: Homan, Philipp, Lin, Qi, Murrough, James W., Soleimani, Laili, Bach, Dominik R., Clem, Roger L., Schiller, Daniela
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cold Spring Harbor Laboratory Press 2017
Ábhair:
Brief Communication
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647929/
https://ncbi.nlm.nih.gov/pubmed/29038221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.045898.117
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