TIAM1 inhibits lung fibroblast differentiation in pulmonary fibrosis

The differentiation of fibroblasts to myofibroblasts is critical for the development of idiopathic pulmonary fibrosis (IPF). T-cell lymphoma invasion and metastasis 1 (TIAM1) is known to be associated with amyotrophic lateral sclerosis 1 and colorectal cancer; however, its role in IPF is unclear. Th...

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Veröffentlicht in:Exp Ther Med
Hauptverfasser: Huang, Zhicheng, Sun, Shuangyan, Yang, Changliang, Zheng, Jun, Nan, Yingji, Zhao, Ruikun, Lang, Zhiguo, Li, Hang, Ma, Lixia
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2017
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647702/
https://ncbi.nlm.nih.gov/pubmed/29067109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.5024
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