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I-BET151 inhibits expression of RANKL, OPG, MMP3 and MMP9 in ankylosing spondylitis in vivo and in vitro

Ankylosing spondylitis (AS) is characterized by osteoclastogenesis and inflammatory bone resorption. The present study aimed to investigate the effect of bromodomain and extra-terminal domain (BET) protein inhibitor I-BET151 on AS process. A total of 38 AS Chinese patients were recruited and a furth...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Fan, Jianping, Zhao, Jian, Shao, Jie, Wei, Xianzhao, Zhu, Xiaodong, Li, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647692/
https://ncbi.nlm.nih.gov/pubmed/29067128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.5032
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