Angiotensin receptor blockade improves cardiac mitochondrial activity in response to an acute glucose load in obese insulin resistant rats

Hyperglycemia increases the risk of oxidant overproduction in the heart through activation of a multitude of pathways. Oxidation of mitochondrial enzymes may impair their function resulting in accumulation of intermediates and reverse electron transfer, contributing to mitochondrial dysfunction. Fur...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Thorwald, Max, Rodriguez, Ruben, Lee, Andrew, Martinez, Bridget, Peti-Peterdi, Janos, Nakano, Daisuke, Nishiyama, Akira, Ortiz, Rudy M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647524/
https://ncbi.nlm.nih.gov/pubmed/29049981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.10.005
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