Angiotensin receptor-mediated oxidative stress is associated with impaired cardiac redox signaling and mitochondrial function in insulin-resistant rats

Activation of angiotensin receptor type 1 (AT1) contributes to NADPH oxidase (Nox)-derived oxidative stress during metabolic syndrome. However, the specific role of AT1 in modulating redox signaling, mitochondrial function, and oxidative stress in the heart remains more elusive. To test the hypothes...

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Detalhes bibliográficos
Main Authors: Vázquez-Medina, José Pablo, Popovich, Irina, Thorwald, Max A., Viscarra, Jose A., Rodriguez, Ruben, Sonanez-Organis, Jose G., Lam, Lisa, Peti-Peterdi, Janos, Nakano, Daisuke, Nishiyama, Akira, Ortiz, Rudy M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Integrative Cardiovascular Physiology and Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891241/
https://ncbi.nlm.nih.gov/pubmed/23771688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00101.2013
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