The WNT target SP5 negatively regulates WNT transcriptional programs in human pluripotent stem cells

The WNT/β-catenin signaling pathway is a prominent player in many developmental processes, including gastrulation, anterior–posterior axis specification, organ and tissue development, and homeostasis. Here, we use human pluripotent stem cells (hPSCs) to study the dynamics of the transcriptional resp...

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Udgivet i:Nat Commun
Main Authors: Huggins, Ian J., Bos, Tomas, Gaylord, Olivia, Jessen, Christina, Lonquich, Brianna, Puranen, Angeline, Richter, Jenna, Rossdam, Charlotte, Brafman, David, Gaasterland, Terry, Willert, Karl
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647328/
https://ncbi.nlm.nih.gov/pubmed/29044119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01203-1
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