Chronic drug‐induced effects on contractile motion properties and cardiac biomarkers in human induced pluripotent stem cell‐derived cardiomyocytes

BACKGROUND AND PURPOSE: In the pharmaceutical industry risk assessments of chronic cardiac safety liabilities are mostly performed during late stages of preclinical drug development using in vivo animal models. Here, we explored the potential of human induced pluripotent stem cell‐derived cardiomyoc...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Kopljar, Ivan, De Bondt, An, Vinken, Petra, Teisman, Ard, Damiano, Bruce, Goeminne, Nick, Van den Wyngaert, Ilse, Gallacher, David J, Lu, Hua Rong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Themed Section: Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647189/
https://ncbi.nlm.nih.gov/pubmed/28094846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13713
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados