SEIPIN Regulates Lipid Droplet Expansion and Adipocyte Development by Modulating the Activity of Glycerol-3-phosphate Acyltransferase

Berardinelli-Seip congenital lipodystrophy 2 (BSCL2) is caused by loss-of-function mutations in SEIPIN, a protein implicated in both adipogenesis and lipid droplet expansion but whose molecular function remains obscure. Here, we identify physical and functional interactions between SEIPIN and micros...

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Veröffentlicht in:Cell Rep
Hauptverfasser: Pagac, Martin, Cooper, Daniel E., Qi, Yanfei, Lukmantara, Ivan E., Mak, Hoi Yin, Wu, Zengying, Tian, Yuan, Liu, Zhonghua, Lei, Mona, Du, Ximing, Ferguson, Charles, Kotevski, Damian, Sadowski, Pawel, Chen, Weiqin, Boroda, Salome, Harris, Thurl E., Liu, George, Parton, Robert G., Huang, Xun, Coleman, Rosalind A., Yang, Hongyuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647143/
https://ncbi.nlm.nih.gov/pubmed/27806294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.10.037
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