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Methylation of mitochondrial DNA displacement loop region regulates mitochondrial copy number in colorectal cancer

It is not established whether de-methylation of the displacement loop (D-loop) region if mitochondrial DNA (mtDNA) directly influences mtDNA copy number and further alters the cell cycle, apoptosis and cell proliferation in colorectal cancer. The current study employed cell viability assays, cell cy...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Tong, Huan, Zhang, Linhao, Gao, Jinhang, Wen, Shilei, Zhou, Hongying, Feng, Shi
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5647067/
https://ncbi.nlm.nih.gov/pubmed/28849075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.7264
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