Beclin 1 overexpression inhibits chondrocyte apoptosis and downregulates extracellular matrix metabolism in osteoarthritis

In the present study, the expression of Beclin 1 in osteoarthritis (OA) cartilage tissue was investigated, and also its role in proliferation, apoptosis and expression of matrix metalloproteinases (MMPs) in chondrocytes obtained from patients with OA. Beclin 1 expression in cartilage tissue from OA...

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Vydáno v:Mol Med Rep
Hlavní autoři: Song, Bin, Song, Hong, Wang, Weiguo, Wang, Hongru, Peng, Hanyuan, Cui, Jing, Wang, Rong, Huang, Hua, Wang, Wei, Wang, Lili
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2017
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5646975/
https://ncbi.nlm.nih.gov/pubmed/28731147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.7064
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