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The utility of empirically assigning ancestry groups in cross-population genetic studies of addiction

BACKGROUND AND OBJECTIVES: Given moderate heritability and significant heterogeneity among addiction phenotypes, successful genome-wide association studies (GWAS) are expected to need very large samples. As sample sizes grow, so can genetic diversity leading to challenges in analyzing these data. Me...

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書誌詳細
出版年:Am J Addict
主要な著者: Peterson, Roseann E., Edwards, Alexis C., Bacanu, Silviu-Alin, Dick, Danielle M., Kendler, Kenneth S., Webb, Bradley T.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5646819/
https://ncbi.nlm.nih.gov/pubmed/28714599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajad.12586
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