Generation and characterisation of Porphyromonas gingivalis mutant lacking peptidylarginine deiminase activity

Porphyromonas gingivalis peptidylarginine deiminase (PPAD) is the focus of several studies due to its ability to citrullinate in vitro human proteins, which have been linked to the aetiopathogenesis of rheumatoid arthritis (RA). The aim of this work was the generation by homologous recombination and...

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Veröffentlicht in:J Oral Microbiol
Hauptverfasser: Muñoz-Atienza, Estefanía, Aduse-Opoku, Joseph, Flak, Magdalena B., Paramonov, Nikolay A., Pitzalis, Costantino, Curtis, Michael A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5646602/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/20002297.2017.1325258
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