Small molecule modulation of splicing factor expression is associated with rescue from cellular senescence

BACKGROUND: Altered expression of mRNA splicing factors occurs with ageing in vivo and is thought to be an ageing mechanism. The accumulation of senescent cells also occurs in vivo with advancing age and causes much degenerative age-related pathology. However, the relationship between these two proc...

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Detalhes bibliográficos
Publicado no:BMC Cell Biol
Main Authors: Latorre, Eva, Birar, Vishal C., Sheerin, Angela N., Jeynes, J. Charles C., Hooper, Amy, Dawe, Helen R., Melzer, David, Cox, Lynne S., Faragher, Richard G. A., Ostler, Elizabeth L., Harries, Lorna W.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645932/
https://ncbi.nlm.nih.gov/pubmed/29041897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-017-0147-7
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