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Grapiprant: an EP4 prostaglandin receptor antagonist and novel therapy for pain and inflammation

There are five active prostanoid metabolites of arachidonic acid (AA) that have widespread and varied physiologic functions throughout the body, including regulation of gastrointestinal mucosal blood flow, renal haemodynamics and primary haemostasis. Each prostanoid has at least one distinct recepto...

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Détails bibliographiques
Publié dans:Vet Med Sci
Auteurs principaux: Kirkby Shaw, Kristin, Rausch‐Derra, Lesley C., Rhodes, Linda
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645826/
https://ncbi.nlm.nih.gov/pubmed/29067176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/vms3.13
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