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Grapiprant: an EP4 prostaglandin receptor antagonist and novel therapy for pain and inflammation

There are five active prostanoid metabolites of arachidonic acid (AA) that have widespread and varied physiologic functions throughout the body, including regulation of gastrointestinal mucosal blood flow, renal haemodynamics and primary haemostasis. Each prostanoid has at least one distinct recepto...

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Detalhes bibliográficos
Publicado no:Vet Med Sci
Main Authors: Kirkby Shaw, Kristin, Rausch‐Derra, Lesley C., Rhodes, Linda
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645826/
https://ncbi.nlm.nih.gov/pubmed/29067176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/vms3.13
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