Deletion of the Mineralocorticoid Receptor in Myeloid Cells Attenuates Central Nervous System Autoimmunity

Myeloid cells play an important role in the pathogenesis of multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE). Monocytes, macrophages, and microglia can adopt two distinct phenotypes, with M1-polarized cells being more related to inflammation and autoimmuni...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Montes-Cobos, Elena, Schweingruber, Nils, Li, Xiao, Fischer, Henrike J., Reichardt, Holger M., Lühder, Fred
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645513/
https://ncbi.nlm.nih.gov/pubmed/29081780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01319
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