Abnormal M1/M2 macrophage phenotype profiles in the small airway wall and lumen in smokers and chronic obstructive pulmonary disease (COPD)

We explore potential dysregulation of macrophage phenotypes in COPD pathogenesis through integrated study of human small airway tissue, bronchoalveolar lavage (BAL) and an experimental murine model of COPD. We evaluated human airway tissue and BAL from healthy controls, normal lung function smokers...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Eapen, Mathew Suji, Hansbro, Philip M., McAlinden, Kielan, Kim, Richard Y., Ward, Chris, Hackett, Tillie-Louise, Walters, Eugene H., Sohal, Sukhwinder Singh
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645352/
https://ncbi.nlm.nih.gov/pubmed/29042607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13888-x
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