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Knockout of maternal CD163 protects fetuses from infection with porcine reproductive and respiratory syndrome virus (PRRSV)

After infection of the porcine dam at about 90 days of gestation, porcine reproductive and respiratory syndrome virus (PRRSV) crosses the placenta and begins to infect fetuses. Outcomes of include abortion, fetal death and respiratory disease in newborn piglets. CD163 is the receptor for the virus....

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Prather, Randall S., Wells, Kevin D., Whitworth, Kristin M., Kerrigan, Maureen A., Samuel, Melissa S., Mileham, Alan, Popescu, Luca N., Rowland, Raymond R. R.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645351/
https://ncbi.nlm.nih.gov/pubmed/29042674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13794-2
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