Binding of a C-type lectin’s coiled-coil domain to the Domeless receptor directly activates the JAK/STAT pathway in the shrimp immune response to bacterial infection

C-type lectins (CTLs) are characterized by the presence of a C-type carbohydrate recognition domain (CTLD) that by recognizing microbial glycans, is responsible for their roles as pattern recognition receptors in the immune response to bacterial infection. In addition to the CTLD, however, some CTLs...

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Bibliographic Details
Published in:PLoS Pathog
Main Authors: Sun, Jie-Jie, Lan, Jiang-Feng, Zhao, Xiao-Fan, Vasta, Gerardo R., Wang, Jin-Xing
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645147/
https://ncbi.nlm.nih.gov/pubmed/28931061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006626
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