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Evaluating the therapeutic potential of idebenone and related quinone analogues in Leber hereditary optic neuropathy
Leber hereditary optic neuropathy (LHON) is an important cause of mitochondrial blindness among young adults. In this study, we investigated the potential of four quinone analogues (CoQ(1), CoQ(10), decylubiquinone and idebenone) in compensating for the deleterious effect of the m.11778G>A mitoch...
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| Pubblicato in: | Mitochondrion |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier Science
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5644719/ https://ncbi.nlm.nih.gov/pubmed/28093355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2017.01.004 |
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