A randomized placebo-controlled trial of idebenone in Leber’s hereditary optic neuropathy

Major advances in understanding the pathogenesis of inherited metabolic disease caused by mitochondrial DNA mutations have yet to translate into treatments of proven efficacy. Leber’s hereditary optic neuropathy is the most common mitochondrial DNA disorder causing irreversible blindness in young ad...

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Huvudupphovsmän: Klopstock, Thomas, Yu-Wai-Man, Patrick, Dimitriadis, Konstantinos, Rouleau, Jacinthe, Heck, Suzette, Bailie, Maura, Atawan, Alaa, Chattopadhyay, Sandip, Schubert, Marion, Garip, Aylin, Kernt, Marcus, Petraki, Diana, Rummey, Christian, Leinonen, Mika, Metz, Günther, Griffiths, Philip G., Meier, Thomas, Chinnery, Patrick F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2011
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Original Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170530/
https://ncbi.nlm.nih.gov/pubmed/21788663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awr170
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