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GBPs Inhibit Motility of Shigella flexneri but Are Targeted for Degradation by the Bacterial Ubiquitin Ligase IpaH9.8

Interferon exposure boosts cell-autonomous immunity for more efficient pathogen control. But how interferon-enhanced immunity protects the cytosol against bacteria and how professionally cytosol-dwelling bacteria avoid clearance are insufficiently understood. Here we demonstrate that the interferon-...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Wandel, Michal P., Pathe, Claudio, Werner, Emma I., Ellison, Cara J., Boyle, Keith B., von der Malsburg, Alexander, Rohde, John, Randow, Felix
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5644667/
https://ncbi.nlm.nih.gov/pubmed/29024643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2017.09.007
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