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Comparative Aspects of BRAF Mutations in Canine Cancers
Activating mutations of the BRAF gene lead to constitutive activation of the MAPK pathway. The characterization and discovery of BRAF mutations in a variety of human cancers has led to the development of specific inhibitors targeting the BRAF/MAPK pathway and dramatically changed clinical outcomes i...
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| Veröffentlicht in: | Vet Sci |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5644641/ https://ncbi.nlm.nih.gov/pubmed/29061943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vetsci2030231 |
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