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Comparative Aspects of BRAF Mutations in Canine Cancers

Activating mutations of the BRAF gene lead to constitutive activation of the MAPK pathway. The characterization and discovery of BRAF mutations in a variety of human cancers has led to the development of specific inhibitors targeting the BRAF/MAPK pathway and dramatically changed clinical outcomes i...

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Detalhes bibliográficos
Publicado no:Vet Sci
Main Authors: Mochizuki, Hiroyuki, Breen, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5644641/
https://ncbi.nlm.nih.gov/pubmed/29061943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vetsci2030231
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