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REVEALing the effect of CETP inhibition in cardiovascular disease

Initial randomized trials of cholesteryl ester transfer protein (CETP) inhibitors were terminated early owing to adverse effects or futility. The REVEAL trial now shows the benefit of CETP inhibition in coronary heart disease. Despite raising HDL-cholesterol levels, the cardiovascular effect of CETP...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nat Rev Cardiol
Hauptverfasser: Holmes, Michael V, Davey Smith, George
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5644574/
https://ncbi.nlm.nih.gov/pubmed/28980665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrcardio.2017.156
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