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Randomized open-label trial of dextromethorphan in Rett syndrome

OBJECTIVE: To determine safety and perform a preliminary assessment of dose-dependent efficacy of dextromethorphan in normalizing electrographic spikes, clinical seizures, and behavioral and cognitive functions in girls with Rett syndrome. METHODS: We used a prospective randomized, open-label trial...

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Bibliografiske detaljer
Udgivet i:Neurology
Main Authors: Smith-Hicks, Constance L., Gupta, Siddharth, Ewen, Joshua B., Hong, Manisha, Kratz, Lisa, Kelley, Richard, Tierney, Elaine, Vaurio, Rebecca, Bibat, Genila, Sanyal, Abanti, Yenokyan, Gayane, Brereton, Nga, Johnston, Michael V., Naidu, Sakkubai
Format: Artigo
Sprog:Inglês
Udgivet: Lippincott Williams & Wilkins 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5644464/
https://ncbi.nlm.nih.gov/pubmed/28931647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000004515
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