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Randomized open-label trial of dextromethorphan in Rett syndrome

OBJECTIVE: To determine safety and perform a preliminary assessment of dose-dependent efficacy of dextromethorphan in normalizing electrographic spikes, clinical seizures, and behavioral and cognitive functions in girls with Rett syndrome. METHODS: We used a prospective randomized, open-label trial...

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Bibliografiska uppgifter
I publikationen:Neurology
Huvudupphovsmän: Smith-Hicks, Constance L., Gupta, Siddharth, Ewen, Joshua B., Hong, Manisha, Kratz, Lisa, Kelley, Richard, Tierney, Elaine, Vaurio, Rebecca, Bibat, Genila, Sanyal, Abanti, Yenokyan, Gayane, Brereton, Nga, Johnston, Michael V., Naidu, Sakkubai
Materialtyp: Artigo
Språk:Inglês
Publicerad: Lippincott Williams & Wilkins 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5644464/
https://ncbi.nlm.nih.gov/pubmed/28931647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000004515
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