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Haloperidol inactivates AMPK and reduces tau phosphorylation in a tau mouse model of Alzheimer's disease

INTRODUCTION: The use of antipsychotic medications in Alzheimer's disease has been associated with an increased risk of mortality in clinical trials. However, an older postmortem literature suggests that those with schizophrenia treated in an era of exclusively conventional antipsychotic medica...

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Enregistré dans:
Détails bibliographiques
Publié dans:Alzheimers Dement (N Y)
Auteurs principaux: Koppel, Jeremy, Jimenez, Heidy, Adrien, Leslie, Greenwald, Blaine S., Marambaud, Philippe, Cinamon, Ezra, Davies, Peter
Format: Artigo
Langue:Inglês
Publié: Elsevier 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5644277/
https://ncbi.nlm.nih.gov/pubmed/29067299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trci.2016.05.003
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