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Human Cardiomyocyte Progenitor Cells in Co-culture with Rat Cardiomyocytes Form a Pro-arrhythmic Substrate: Evidence for Two Different Arrhythmogenic Mechanisms

Background: Cardiomyocyte progenitor cells (CMPCs) are a promising cell source for regenerative cell therapy to improve cardiac function after myocardial infarction. However, it is unknown whether undifferentiated CMPCs have arrhythmogenic risks. We investigate whether undifferentiated, regionally a...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Smit, Nicoline W., Cócera Ortega, Lucia, Végh, Anna M. D., Meijborg, Veronique M. F., Smits, Anke M., Klerk, Mischa, Tijsen, Anke J. M., Tan, Hanno L., Goumans, Marie-José H. T., Boink, Gerard J. J., Coronel, Ruben
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5644204/
https://ncbi.nlm.nih.gov/pubmed/29075204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00797
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