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Cardiomyocyte Progenitor Cells as a Functional Gene Delivery Vehicle for Long-Term Biological Pacing

Sustained pacemaker function is a challenge in biological pacemaker engineering. Human cardiomyocyte progenitor cells (CMPCs) have exhibited extended survival in the heart after transplantation. We studied whether lentivirally transduced CMPCs that express the pacemaker current I(f) (encoded by HCN4...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Végh, Anna M. D., den Haan, A. Dénise, Cócera Ortega, Lucía, Verkerk, Arie O., Sluijter, Joost P. G., Bakker, Diane, van Amersfoorth, Shirley, van Veen, Toon A. B., Klerk, Mischa, Seppen, Jurgen, de Bakker, Jacques M. T., Christoffels, Vincent M., Geerts, Dirk, Goumans, Marie José T. H., Tan, Hanno L., Boink, Gerard J. J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337610/
https://ncbi.nlm.nih.gov/pubmed/30621310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24010181
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