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Generalized disequilibrium test for association in qualitative traits incorporating imprinting effects based on extended pedigrees

BACKGROUND: For dichotomous traits, the generalized disequilibrium test with the moment estimate of the variance (GDT-ME) is a powerful family-based association method. Genomic imprinting is an important epigenetic phenomenon and currently, there has been increasing interest of incorporating imprint...

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Détails bibliographiques
Publié dans:BMC Genet
Auteurs principaux: Li, Jian-Long, Wang, Peng, Fung, Wing Kam, Zhou, Ji-Yuan
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5644153/
https://ncbi.nlm.nih.gov/pubmed/29037145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-017-0560-0
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